Artemisia annua prefers consistently moist soil but can tolerate brief periods of drought once established. Water deeply when the top inch of soil feels dry.

Avoid overwatering, which can lead to root rot, especially in poorly draining soil. Reduce watering in cooler months.

Prune Artemisia annua in early spring to shape the plant and encourage bushier growth. Deadheading spent flowers can prevent self-seeding and prolong the blooming period.

Light trimming throughout the growing season can maintain a tidy appearance. Remove any dead or damaged stems promptly.

Artemisia annua is easily propagated by seeds sown in early spring, either directly outdoors after the last frost or indoors a few weeks prior.

Cuttings taken in late spring or early summer can also be rooted in moist, well-draining soil or perlite. Division of established clumps in spring is also effective.

Repotting is rarely necessary for Artemisia annua, as it prefers to be slightly root-bound and can grow in less than ideal conditions. If grown in a container and the plant becomes excessively large or outgrows its pot, repot in spring into a slightly larger container with fresh, well-draining potting mix.