Lentisk is highly drought-tolerant once established, requiring minimal watering. During its first year, water regularly to help establish roots, especially in dry periods. Mature plants in Mediterranean climates typically thrive on natural rainfall, needing supplemental water only during prolonged, severe droughts. Avoid overwatering, which can lead to root rot.

Prune Lentisk to maintain shape, remove dead or diseased branches, or control size. The best time for pruning is late winter or early spring before new growth begins. It tolerates hard pruning well, making it suitable for hedging or topiary. For mastic production, specific pruning techniques are used to encourage resin flow.

Lentisk can be propagated by seeds, cuttings, or layering. Seeds require stratification for germination. Semi-hardwood cuttings taken in late summer or early autumn root best with the aid of rooting hormone and bottom heat. Air layering can also be successful, offering a reliable method for producing larger plants.

Repotting is generally not applicable for mature, outdoor-grown Lentisk as it is a large shrub or small tree. If grown in a container when young, repot every 2-3 years into a slightly larger pot with fresh, well-draining potting mix. Ensure the new pot has adequate drainage holes.