Circaea lutetiana prefers consistently moist soil, especially during dry periods. Water deeply when the top few centimeters of soil feel dry to the touch, but ensure good drainage to prevent waterlogging, which can lead to root rot. Regular watering is crucial for establishment and during active growth in summer.

Minimal pruning is needed for this plant. Dead or damaged foliage can be removed to maintain tidiness and plant health. To control its spread, especially in garden settings where it can be vigorous, cut back runners or unwanted growth in late summer or autumn. This also helps prevent excessive self-seeding.

Broadleaf Enchanter's-nightshade is easily propagated by division of its rhizomatous rootstock in spring or autumn. Simply dig up a clump and separate sections with roots and shoots. Seeds can also be collected from the burr-like fruits and sown, though germination can be erratic and slower.

This plant is not typically grown in pots due to its spreading nature. If, however, it is cultivated in a container for specific reasons, repotting would be necessary when the plant becomes root-bound, usually every 1-2 years. Use a slightly larger pot with fresh, humus-rich, well-draining soil.